Area A

Pathogen recognition in the lung and initiation of innate immune response

Area B

Humoral and cell-based bronchoalveolar defense mechanisms

Area C

Control of host response in the bronchoalveolar compartment and strategies for intervention

A1 – Opitz / Diefenbach

Regulation of antibacterial defense in the lung by the alarmin IL-33

B2 – Peteranderl / Wolff

Stabilization of epithelial integrity in influenza virus pneumonia: role of death ligands and their downstream effectors

C1 – Schmeck / Marsico

RNA-mediated regulatory networks in Legionella pneumophila pneumonia

A2 – Wygrecka / Kübler / Hackstein

Coagulation factor XII – a  novel regulator of immune responses and barrier function in pneumonia

A4 – Pillich / Chakraborty / Hippenstiel

Pathophysiological host-pathogen crosstalk of Streptococcus pneumoniae at lung barrier interfaces

B6 – Hocke /Hippenstiel / Antelmann

Bacterial acidification as a new virulence mechanism for immune activation and barrier failure via mitochondrial dysfunction

C6 – Witzenrath / Weissmann

Lung protection in severe pneumonia by means of Tie2 agonism

A5 – Opitz / Chaput / Heimesaat

Cross-talk of antimicrobial therapy, microbiota and innate immunity in pneumonia

C8 – Seeberger / Sander

Novel glyco-conjugate vaccine strategies against bacterial pneumonia

A6 – Kummer / Diefenbach

Pathogen recognition by taste and odorant receptors and coupling to BALT formation and epithelial remodeling

B8 – Hain / Mall

Therapeutic targeting of airway microbiome in mice with cystic fibrosis-like lung disease to prevent lung damage and pneumonia

C9 – Kübler / Suttorp / Witzenrath

Role of CFTR and its downstream signaling in lung barrier failure in pneumonia

A7 – Drosten / Hönzke

Modulation of infection and defense by MERS-coronavirus protein 4b

B9 – Herold / Triantafyllopulou

Regulation of macrophage reprogramming and functional specification in pneumonia

C10 – Sander / Schulte / Bauer

Long non-coding RNAs and RNA editing in antibacterial host defense in the lung

Area Z: Service Projects

Z1a – Hocke

High-end microscopy and digital image analysis in cellular microbiology of the lung

Z1b – Gruber

Experimental histopathology, advanced histomorphometrical digital image analysis, molecular pathology and tissue banking